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| Idiosyncrasy |
| | An abnormal sensitivity to some drug or other substance which is peculiar to the individual. |
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| IDLH |
| | Immediately Dangerous to Life and Health. A NIOSH estimate for the maximum level of exposure from which a person could exit in 30 minutes without escape-impairing symptoms or irreversible health effects. |
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| Immunotoxicity |
| | Toxicity of the immune system. It may take several forms: hypersensitivity (allergy and autoimmunity), immunodeficiency, and uncontrolled proliferation (leukemia and lymphoma). |
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| In Vitro |
| | Outside a living organism (e.g., in a test tube). |
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| In Vivo |
| | Occurring within a living organism. |
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| Interactions |
| | Refers to measures of effects of simultaneous exposure to two or more substances. The four types of interactions are: additive, antagonistic, potentiation, or synergistic. |
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| Investigational New Drug Application (IND) |
| | Application submitted to the FDA by a pharmaceutical company requesting permission to undertake clinical investigations of a test drug in humans. |
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| Irritation |
| | Local tissue reaction without involvement of an immunologic mechanism. It is a reversible inflammation. |
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| Isomer |
| | A structurally different form of a chemical having the same molecular formula. |
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