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modifications in absorption, metabolism, or excretion, reactions at binding sites and receptors, and specific physiological changes.

There are four basic types of interactions based on expected responses of the individual chemicals. These are: additivity, antagonism, potentiation, and synergism.

An additivity reaction results when the response to a combination of two or more chemicals is equal to the sum of the individual responses. This is the most common type of drug interaction. For
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